Title : Association of LRP 5 genotypes with osteoporosis in
نویسندگان
چکیده
1 Osteoporosis and Arthritis laboratory, Rabta hospital, Faculty of Medicine of Tunis, Tunis EL Manar University, Tunisia 2 Division of Bone Diseases, Rehabilitation and Geriatrics Department , Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland 3 Genetics, immunology and human pathologies Laboratory, Faculty of Mathematical, Physical and Natural Sciences of Tunis, Tunis EL Manar University, Tunisia
منابع مشابه
Lack of Association of CYP2E1 and CYP1A1 Polymorphisms With Osteoporosis in Postmenauposal Women
Osteoporosis is a metabolic bone disease affecting mostly elderly women. As metabolizing enzymes, the roles of few cytochromes have been studied in osteoporosis development. The aim of this study was to assess for the first time the association of CYP2E1 and CYP1A1 polymorphisms and osteoporosis in postmenopausal women. 112 postmenopausal women presenting osteoporosis and 93 age and sex matched...
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Background: Osteoporosis as a multifactorial disease caused by decreased bone mineral density (BMD) especially calcium increasing fracture risk. Vitamin D binding protein (VDBP or Gc) is a molecule key to the biologic actions of vitamin D. Mutation in some critical areas of VDBP can affect metabolism of minerals specially calcium that are important in bone density. This study investigated assoc...
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Introduction: Osteoporosis is a multifactorial disease that leads to etiology leading to morbidity and economical disturbances. This study designed to evaluate the prevalence of osteoporosis in patients referred to Gorgan’s densitometry centers with respect to age, gender and BMI. Methods: In this descriptive-analytic study, from 3000 subjects referred to the densitometry centers of Gorg...
متن کاملAssociation of LRP5 genotypes with osteoporosis in Tunisian post-menopausal women
BACKGROUND Osteoporosis is a highly heritable trait. Among the genes associated with bone mineral density (BMD), the low-density lipoprotein receptor-related protein 5 gene (LRP5) has been consistently identified in Caucasians. However LRP5 contribution to osteoporosis in populations of other ethnicities remains poorly known. METHODS To determine whether LRP5 polymorphisms Ala1330Val and Val6...
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Background: Ageing of population worldwide will be responsible for a major increase of the incidence of osteoporosis in elderly. For the individual, osteoporotic fractures result in great disability as well as loss of quality of life and also represent an enormous burden for healthcare systems. This study was conducted to determine the prevalence of osteoporosis and it's association with serum ...
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تاریخ انتشار 2012